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Preterm birth is the birth of an infant before 37 weeks of gestation
A Global Burden.
10%
of all births are preterm
15 million
babies are born preterm worldwide annually
1 million
do not survive their first month
8.5%
increase in the global rate of preterm birth from year 2000 to 2014
50%
of all neonatal mortality are due to preterm birth
USD 26 billion
worth of socioeconomic burden in the U.S.
Worldwide prevalence of preterm birth
Preterm Birth Rates
Source: Chawanpaiboon, S., Vogel, J. P., Moller, A.-B., Lumbiganon, P., Petzold, M., Hogan, D., … Gülmezoglu, A. M. (2019). Global, regional, and national estimates of levels of preterm birth in 2014: a systematic review and modelling analysis. The Lancet Global Health, 7(1)
Map: http://gun.co.nz/map
An unmet need
Medical Cost of Preterm Birth
The medical cost of preterm cost is immense. In the United States, the average cost of preterm birth (USD 32,325) is 10 times higher than term birth (USD 3325). This translate to a total economic cost of USD 26 billion in the United States.
Preterm Birth
Term Birth
USD 3325
USD 32,325
![shutterstock_375346387 [Converted]-01.pn](https://static.wixstatic.com/media/a7f256_93a8c7b2536e423bb7b1ac0af367aaba~mv2_d_1209_1780_s_2.png/v1/fill/w_268,h_395,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/shutterstock_375346387%20%5BConverted%5D-01_pn.png)
Importance of early prediction
The early identification of women at risk of preterm birth will allow physicians to administer proper treatments to delay the onset of labor and to protect the infant
![shutterstock_1101083204 [Converted]-01.p](https://static.wixstatic.com/media/a7f256_97972d97bf3d43ccb92d63c1bbf60744~mv2.png/v1/fill/w_381,h_255,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/shutterstock_1101083204%20%5BConverted%5D-01_p.png)
Prophylactics
Progesterone supplementation and cervical cerclage
Tocolytics
Uterine activity suppressor
Tocolytics
Corticosteriod and magnesium sulphate
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